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犬异位胰腺同种异体移植的内分泌功能。II. 移植后即刻阶段。

Endocrine function of the heterotopic pancreatic allotransplant in dogs. II. Immediate post-transplant period.

作者信息

Bewick M, Mundy A R, Eaton B, Watson F

出版信息

Transplantation. 1981 Jan;31(1):19-22. doi: 10.1097/00007890-198101000-00005.

DOI:10.1097/00007890-198101000-00005
PMID:6785907
Abstract

Pancreatic endocrine function was investigated in dogs after heterotopic pancreatic allotransplantation. A marked hyperinsulinemia was found in peripheral venous blood within the first 60 min postoperatively. This was associated with hypoglycemia and hypokalemia occurring within the next 2 to 3 hr resulting eventually in death. The hypoglycemia could be corrected by parenteral dextrose and potassium given during the first 2 hr postoperatively or prevented by parenteral hydrocortisone given at the time of transplantation.

摘要

对犬异位胰腺同种异体移植后的胰腺内分泌功能进行了研究。术后最初60分钟内,外周静脉血中出现明显的高胰岛素血症。这与随后2至3小时内发生的低血糖和低钾血症相关,最终导致死亡。术后最初2小时内通过胃肠外给予葡萄糖和钾可纠正低血糖,或在移植时通过胃肠外给予氢化可的松预防低血糖。

相似文献

1
Endocrine function of the heterotopic pancreatic allotransplant in dogs. II. Immediate post-transplant period.犬异位胰腺同种异体移植的内分泌功能。II. 移植后即刻阶段。
Transplantation. 1981 Jan;31(1):19-22. doi: 10.1097/00007890-198101000-00005.
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Endocrine function of the heterotopic pancreatic allotransplant in dogs. I. Normal and rejection.
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Endocrine function of the heterotopic pancreatic allotransplant in dogs.犬异位胰腺同种异体移植的内分泌功能
Transplantation. 1981 Jan;31(1):23-5. doi: 10.1097/00007890-198101000-00006.
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Achievement of insulin independence in three consecutive type-1 diabetic patients via pancreatic islet transplantation using islets isolated at a remote islet isolation center.通过使用在偏远胰岛分离中心分离的胰岛进行胰岛移植,三名1型糖尿病患者连续实现胰岛素自主分泌。
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Neural regulation of heterotopic islets of Langerhans.朗格汉斯异位胰岛的神经调节。
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Auto- and allotransplantation of canine pancreatic tissue.
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[Physiopathology of pancreas transplantation with reference to endocrine function and rejection].[胰腺移植的病理生理学:内分泌功能与排斥反应]
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The effect of transplantation site and islet mass on long-term survival and metabolic and hormonal function of canine purified islet autografts.移植部位和胰岛数量对犬纯化胰岛自体移植长期存活及代谢和激素功能的影响。
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Potassium and endocrine pancreatic function.钾与胰腺内分泌功能。
Nutr Rev. 1974 Jan;32(1):9-12. doi: 10.1111/j.1753-4887.1974.tb06250.x.

引用本文的文献

1
Pancreas and islet transplantation. I. Experimental studies.胰腺和胰岛移植。I. 实验研究。
Diabetologia. 1981 Mar;20(3):161-85. doi: 10.1007/BF00252624.
2
Evaluation of insulin secretion after pancreas autotransplantation by oral or intravenous glucose challenge.通过口服或静脉注射葡萄糖激发试验评估胰腺自体移植后的胰岛素分泌情况。
Ann Surg. 1986 Nov;204(5):585-93. doi: 10.1097/00000658-198611000-00013.
3
Endocrine response to intragastric and intravenous glucose challenge in the denervated dog pancreas.去神经支配的犬胰腺对胃内及静脉注射葡萄糖刺激的内分泌反应。
Int J Pancreatol. 1992 Apr;11(2):117-24. doi: 10.1007/BF02925983.