Marmo E, Ottavo R, Giordano L, Paone G, Falcone O, Spaziante G, Visone C, Campidonico U
Arch Sci Med (Torino). 1980 Jul-Sep;137(3):387-404.
An experimental assessment was made of the analgesic, anti-inflammatory and platelet anticlumping activity of ketoprophene lysine, and its effect on body temperature and prostaglandin synthesis. The drug's pharmacodynamics was very similar to that of ketoprophene and its gastric tolerance was better. It was also well tolerated by the dog joint surfaces and cardiovascular apparatus when given i.m. or i.v., even at doses higher than those advised for man, or when infiltrated in ketoreceptor areas.
对酮洛芬赖氨酸盐的镇痛、抗炎和血小板抗聚集活性，及其对体温和前列腺素合成的影响进行了实验评估。该药物的药效学与酮洛芬非常相似，且其对胃的耐受性更好。当肌肉注射或静脉注射时，即使给予高于人体建议剂量的药物，或在酮受体区域浸润给药时，犬的关节表面和心血管系统对该药物也有良好的耐受性。
