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[切除颈交感神经节对大鼠下丘脑室旁核出生后发育的影响]

[Effect of extirpation of the cervical sympathetic ganglia on the postnatal development of the paraventricular nucleus of the rat hypothalamus].

作者信息

Lepekhina L M

出版信息

Biull Eksp Biol Med. 1978;86(7):107-10.

PMID:678639
Abstract

The importance of trophico-adaptive influences of the sympathetic nervous system for the postnatal hypothalamus development was shown experimentally on rats. Using kario-cytometric method it was found that cervical ganglia extirpation was followed by retarded ontogenetic development of the neurosecretory cells of the paraventricular nucleus, and also by blood vessel changes. The sympathectomy effect coincided with the beginning of an intensive cytoplasm growth in the paraventricular nucleus cells. Sympathectomy proved to be more effective in ratlings than in adult animals.

摘要

通过在大鼠身上进行实验,证明了交感神经系统的营养适应性影响对出生后下丘脑发育的重要性。采用细胞核计数法发现,切除颈神经节后,室旁核神经分泌细胞的个体发育会延迟,同时还会出现血管变化。交感神经切除术的效果与室旁核细胞中细胞质开始大量生长的时间相吻合。事实证明,交感神经切除术对幼鼠的效果比对成年动物更显著。

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