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[大鼠出生后个体发育过程中下丘脑神经分泌细胞发育的形态计量学特征]

[Morphometric characteristics of the development of the neurosecretory cells in the hypothalamic center in the rat during postnatal ontogeny].

作者信息

Danilova O A, Khristich M, Chernigovskaia E V

出版信息

Arkh Anat Gistol Embriol. 1982 Mar;82(3):5-10.

PMID:7092589
Abstract

Neurosecretory cells has been studied in the supraoptic and paraventricular hypothalamic nuclei and in the additional anterocommissural group in rats at 17-80 days of the postnatal development. The cellular functional activity is estimated according to neurosecretion contents in the pericaryon and according to the state of the nucleolar apparatus (volume, amount and position of the nucleoli in the nucleus). The neurosecretory cells complete their formation only by the end of the second postnatal month. The neurosecretory cells of the three hypothalamic centers studied differ by the character of their development. The development of the neurosecretory cells of the anterocommissural group differs considerably from that of the paraventricular and supraoptic nuclear neurosecretory cells, that supports the suggestion about their independent functional role. During the investigation performed especially sharp shifts in the state of the neurosecretory system are noted in the young rats at the age of about 30 days.

摘要

在出生后17 - 80天的大鼠中,对视上核、室旁核以及额外的前连合组中的神经分泌细胞进行了研究。根据核周的神经分泌内容物以及核仁装置的状态(核仁在细胞核中的体积、数量和位置)来评估细胞的功能活性。神经分泌细胞仅在出生后第二个月末才完成其形成。所研究的三个下丘脑中心的神经分泌细胞在发育特征上有所不同。前连合组神经分泌细胞的发育与室旁核和视上核神经分泌细胞的发育有很大差异,这支持了它们具有独立功能作用的观点。在调查过程中,特别注意到约30日龄的幼鼠神经分泌系统状态出现急剧变化。

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