Avtandilov G G, Vasilenko I V
Biull Eksp Biol Med. 1978;86(7):54-7.
Quantitative estimation of the nucleic acids content in the preparations stained with gallocianine-chromic alum was made in 20 cases of stomach cancer. Coefficients of the ratio of the nucleus section surface and the cytoplasm, the ratio of DNA + RNA of the nucleus to RNA of the cytoplasm, and of DNA of the nucleus to the sum total quantity of RNA in the nucleus and the cytoplasm, the index of DNA accumulation were compared in adenocarcinomas (210 cells) and undifferentiated cancers (390 cells) of the stomach. The ratio of the nucleus surface and the cytoplasm, DNA + RNA of the nucleus to RNA of the cytoplasm was higher (statistically significant value) in adenocarcinomas as compared with undifferentiated cancers of the stomach. This allows to suggest a lower differentiation of adenocarcinoma cells in comparison with tumour cells of undifferentiated forms of stomach cancer.
对20例胃癌患者经间苯三酚 - 铬明矾染色的制剂中的核酸含量进行了定量估计。比较了胃腺癌（210个细胞）和未分化癌（390个细胞）中细胞核截面面积与细胞质的比值、细胞核DNA + RNA与细胞质RNA的比值、细胞核DNA与细胞核及细胞质中RNA总量的比值以及DNA积累指数。与胃未分化癌相比，胃腺癌中细胞核面积与细胞质的比值、细胞核DNA + RNA与细胞质RNA的比值更高（具有统计学意义）。这表明与胃未分化癌的肿瘤细胞相比，腺癌细胞的分化程度较低。
