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氟哌啶醇可分泌至母乳中。

Haloperidol secreted in breast milk.

作者信息

Whalley L J, Blain P G, Prime J K

出版信息

Br Med J (Clin Res Ed). 1981 May 30;282(6278):1746-7. doi: 10.1136/bmj.282.6278.1746.

DOI:10.1136/bmj.282.6278.1746
PMID:6786603
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1505716/
Abstract

A nursing mother was given haloperidol 5 mg twice daily for puerperal psychosis and continued to breast feed under hospital supervision. Despite considerable amounts of haloperidol being secreted in the breast milk (up to 23.5 micrograms/l), the infant was apparently not sedated, fed well, and continued to thrive. The findings suggest that maternal ingestion of haloperidol for short periods has no deleterious effect on the infant's development.

摘要

一位哺乳期母亲因产褥期精神病每日两次服用5毫克氟哌啶醇，并在医院监督下继续母乳喂养。尽管母乳中分泌了大量氟哌啶醇（高达23.5微克/升），但婴儿显然未出现镇静作用，喂养良好且持续茁壮成长。这些发现表明，母亲短期摄入氟哌啶醇对婴儿发育没有有害影响。

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本文引用的文献

1
Haloperidol excretion in human milk.
Am J Psychiatry. 1980 Jul;137(7):849-50. doi: 10.1176/ajp.137.7.849.
2
Abnormal ontogeny in young rabbits after chronic administration of haloperidol to the nursing mothers.
Brain Res. 1972 Sep 29;44(2):684-7. doi: 10.1016/0006-8993(72)90336-8.