Salmassi S, Currie E T, Bolf E C, Hernandez M, Kasprisin D O
Cancer. 1981 Jul 15;48(2):252-4. doi: 10.1002/1097-0142(19810715)48:2<252::aid-cncr2820480207>3.0.co;2-m.
A right periauricular swelling developed in a 21-year-old woman with sickle cell anemia. The mass was removed and revealed Hodgkin's disease of the lymphocyte predominance type. While preparing the patient for a staging laparotomy, an allo-anti-Kell and an allo-antic-C were identified in the patient's sera. The patient's direct antiglobulin test was positive and an auto-anti-e was eluted from the patient's erythrocytes. The patient was treated with nine courses of MOPP therapy given over a nine-month period. The clinical and therapeutic implications for the management of patients with sickle cell anemia and lymphoproliferative disorders are discussed.
一名21岁的镰状细胞贫血女性患者出现右耳周肿胀。切除肿块后发现为淋巴细胞为主型霍奇金病。在为患者准备分期剖腹术时,在患者血清中检测到同种抗Kell和同种抗c。患者的直接抗球蛋白试验呈阳性,并且从患者红细胞中洗脱出自体抗e。患者在九个月内接受了九个疗程的MOPP治疗。本文讨论了镰状细胞贫血和淋巴增殖性疾病患者管理的临床及治疗意义。