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淋球菌对玫瑰红菌素的敏感性与青霉素、头孢呋辛和四环素的敏感性比较。

Sensitivity of gonococci to rosoxacin compared with that of penicillin, cefuroxime and tetracycline.

作者信息

Seth A D

出版信息

J Antimicrob Chemother. 1981 Apr;7(4):331-4. doi: 10.1093/jac/7.4.331.

DOI:10.1093/jac/7.4.331
PMID:6788746
Abstract

The in vitro activity of rosoxacin, a pyridyl quinolone derivative against Neisseria gonorrhoeae is compared with that of penicillin, cefuroxime and tetracycline. Three groups of gonococci comprising of beta-lactamase-positive and negative strains and gonococci with high penicillin MICs are studied. Rosoxacin was the most active against the entire spectrum of gonococci tested in vitro and its activity is not affected by the production of beta-lactamase by some gonococci.

摘要

将吡啶基喹诺酮衍生物罗索沙星对淋病奈瑟菌的体外活性与青霉素、头孢呋辛和四环素进行了比较。研究了三组淋球菌，包括β-内酰胺酶阳性和阴性菌株以及青霉素最低抑菌浓度（MIC）高的淋球菌。罗索沙星对体外测试的整个淋球菌谱活性最强，且其活性不受某些淋球菌产生β-内酰胺酶的影响。

相似文献

1
Sensitivity of gonococci to rosoxacin compared with that of penicillin, cefuroxime and tetracycline.淋球菌对玫瑰红菌素的敏感性与青霉素、头孢呋辛和四环素的敏感性比较。
J Antimicrob Chemother. 1981 Apr;7(4):331-4. doi: 10.1093/jac/7.4.331.
2
In-vitro antigonococcal activity of rosoxacin (WIN 35213).罗索沙星（WIN 35213）的体外抗淋球菌活性。
Br J Vener Dis. 1981 Feb;57(1):33-5. doi: 10.1136/sti.57.1.33.
3
[In vitro activity of rosoxacin (Win 35 213) against Neisseria gonorrhoeae (author's transl)].罗索沙星（Win 35213）对淋病奈瑟菌的体外活性（作者译）
Arzneimittelforschung. 1980;30(9):1476-8.
4
Disc sensitivity of gonococci to rosoxacin, tetracycline and beta-lactam antibiotics.淋球菌对玫瑰红菌素、四环素和β-内酰胺类抗生素的药敏情况。
Cent Afr J Med. 1983 Nov;29(11):216-7.
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Comparative in vitro activity of Mk-0366 and other selected oral antimicrobial agents against Neisseria gonorrhoeae.Mk-0366与其他选定口服抗菌剂对淋病奈瑟菌的体外活性比较
Antimicrob Agents Chemother. 1981 Aug;20(2):265-6. doi: 10.1128/AAC.20.2.265.
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In vitro activities of the spectinomycin analog U-63366 and four quinolone derivatives against Neisseria gonorrhoeae.壮观霉素类似物U-63366及四种喹诺酮衍生物对淋病奈瑟菌的体外活性
Antimicrob Agents Chemother. 1984 Oct;26(4):608-9. doi: 10.1128/AAC.26.4.608.
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The activity of rosoxacin, fosfomycin, cefotiam, and spectinomycin on beta-lactamase producing Neisseria gonorrhoeae.罗索沙星、磷霉素、头孢替安和大观霉素对产β-内酰胺酶淋病奈瑟菌的活性。
Br J Vener Dis. 1984 Jun;60(3):154-6. doi: 10.1136/sti.60.3.154.
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In-vitro activity of enoxacin against gonococcal isolates in comparison with that of five other antibiotics.
J Antimicrob Chemother. 1988 Feb;21 Suppl B:43-8. doi: 10.1093/jac/21.suppl_b.43.
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In vitro antimicrobial activity of rosoxacin against Neisseria gonorrhoeae, Chlamydia trachomatis, and Ureaplasma urealyticum.罗索沙星对淋病奈瑟菌、沙眼衣原体和解脲脲原体的体外抗菌活性。
Antimicrob Agents Chemother. 1980 Nov;18(5):738-40. doi: 10.1128/AAC.18.5.738.
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Acrosoxacin-resistant gonococci.耐阿克罗沙星的淋球菌
Lancet. 1982 Apr 10;1(8276):855-6. doi: 10.1016/s0140-6736(82)91905-5.

引用本文的文献

1
In vitro susceptibility and cross-resistance of South African isolates of Neisseria gonorrhoeae to 14 antimicrobial agents.南非淋病奈瑟菌分离株对14种抗菌药物的体外敏感性及交叉耐药性
Antimicrob Agents Chemother. 1982 Oct;22(4):598-603. doi: 10.1128/AAC.22.4.598.
2
Quinolone derivative, flumequine, as short-term treatment for gonorrhoea.喹诺酮衍生物氟甲喹作为淋病的短期治疗药物。
Br J Vener Dis. 1982 Oct;58(5):317-20. doi: 10.1136/sti.58.5.317.
3
Influence of inoculum size on comparative susceptibilities of penicillinase-positive and -negative Neisseria gonorrhoeae to 31 antimicrobial agents.
接种量对青霉素酶阳性和阴性淋病奈瑟菌对31种抗菌药物敏感性比较的影响
Antimicrob Agents Chemother. 1984 Aug;26(2):192-5. doi: 10.1128/AAC.26.2.192.
4
Treatment of uncomplicated gonorrhoea with rosoxacin (acrosoxacin).用咯索沙星（阿克索沙星）治疗单纯性淋病。
Br J Vener Dis. 1984 Jun;60(3):157-60. doi: 10.1136/sti.60.3.157.
5
Rosoxacin in the treatment of uncomplicated gonorrhoea in men.罗索沙星治疗男性单纯性淋病。
Br J Vener Dis. 1984 Aug;60(4):231-4. doi: 10.1136/sti.60.4.231.