抗人肾素单克隆抗体。
Monoclonal antibody against human renin.
作者信息
Simon D, Galen F X, Devaux C, Soubrier F, Pau B, Menard J, Corvol P
出版信息
J Clin Endocrinol Metab. 1981 Aug;53(2):453-5. doi: 10.1210/jcem-53-2-453.
PMID:6788795
Abstract
By spleen cell fusion with NS1 myeloma, a mouse hybridoma was obtained which secretes an antibody directed against human renin. This monoclonal antibody recognizes human and monkey renin, but neither hog nor mouse. Preliminary experiments demonstrate the potential of this antibody for renin immunopurification and characterization.
摘要
通过脾细胞与NS1骨髓瘤细胞融合，获得了一种分泌抗人肾素抗体的小鼠杂交瘤。这种单克隆抗体可识别人和猴的肾素，但不能识别猪和小鼠的肾素。初步实验证明了这种抗体在肾素免疫纯化和鉴定方面的潜力。
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