锥虫中的多胺：含量、合成及功能与化疗的关系 - Suppr

Suppr

超能文献

Content, synthesis, and function of polyamines in trypanosomatids: relationship to chemotherapy.

作者信息

Bacchi C J

出版信息

J Protozool. 1981 Feb;28(1):20-7. doi: 10.1111/j.1550-7408.1981.tb02798.x.

DOI:10.1111/j.1550-7408.1981.tb02798.x

PMID:6788943

Abstract

摘要

相似文献

Content, synthesis, and function of polyamines in trypanosomatids: relationship to chemotherapy.锥虫中的多胺：含量、合成及功能与化疗的关系

J Protozool. 1981 Feb;28(1):20-7. doi: 10.1111/j.1550-7408.1981.tb02798.x.

Polyamine metabolism as chemotherapeutic target in protozoan parasites.多胺代谢作为原生动物寄生虫化疗靶点

Mini Rev Med Chem. 2002 Dec;2(6):553-63. doi: 10.2174/1389557023405549.

Targeting polyamines of parasitic protozoa in chemotherapy.化疗中针对寄生原生动物多胺的研究

Trends Parasitol. 2001 May;17(5):242-9. doi: 10.1016/s1471-4922(01)01908-0.

Ureotelism and ammonotelism in trypanosomatids.锥虫中的尿素排泄和氨排泄

J Bacteriol. 1978 Dec;136(3):1184-6. doi: 10.1128/jb.136.3.1184-1186.1978.

Polyamines in trypanosomatids.锥虫中的多胺

J Bacteriol. 1977 Aug;131(2):657-61. doi: 10.1128/jb.131.2.657-661.1977.

Putrescine and spermidine transport in Leishmania.利什曼原虫中的腐胺和亚精胺转运

Mol Biochem Parasitol. 2000 Jun;109(1):37-46. doi: 10.1016/s0166-6851(00)00234-6.

Kinetoplast as a potential chemotherapeutic target of trypanosomatids.动基体作为锥虫的潜在化疗靶点。

Curr Pharm Des. 2008;14(9):847-54. doi: 10.2174/138161208784041051.

Levels of polyamines, glutathione and glutathione-spermidine conjugates during growth of the insect trypanosomatid Crithidia fasciculata.昆虫锥虫Crithidia fasciculata生长过程中多胺、谷胱甘肽及谷胱甘肽-亚精胺缀合物的水平

J Gen Microbiol. 1988 Mar;134(3):807-17. doi: 10.1099/00221287-134-3-807.

Polyamines in Trichomonas vaginalis.

Mol Biochem Parasitol. 1983 Dec;9(4):309-18. doi: 10.1016/0166-6851(83)90087-7.

Polyamine synthesis and levels during the growth and replication of Leishmania tropica minor and Leishmania aethiopica.

FEBS Lett. 1979 Oct 1;106(1):202-6. doi: 10.1016/0014-5793(79)80728-0.

引用本文的文献

Comparative metabolism of conjugated and unconjugated pterins in Crithidia, Leishmania and African trypanosomes.克氏锥虫、利什曼原虫和非洲锥虫中共轭蝶呤和非共轭蝶呤的比较代谢

PLoS Negl Trop Dis. 2025 Jul 29;19(7):e0013332. doi: 10.1371/journal.pntd.0013332. eCollection 2025 Jul.

Omics data integration facilitates target selection for new antiparasitic drugs against TriTryp infections.组学数据整合有助于针对锥虫感染筛选新型抗寄生虫药物的靶点。

Front Pharmacol. 2023 Apr 6;14:1136321. doi: 10.3389/fphar.2023.1136321. eCollection 2023.

Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis.用于治疗人类非洲锥虫病的新型S-腺苷甲硫氨酸脱羧酶抑制剂。

Antimicrob Agents Chemother. 2009 May;53(5):2052-8. doi: 10.1128/AAC.01674-08. Epub 2009 Mar 16.

The ornithine decarboxylase domain of the bifunctional ornithine decarboxylase/S-adenosylmethionine decarboxylase of Plasmodium falciparum: recombinant expression and catalytic properties of two different constructs.恶性疟原虫双功能鸟氨酸脱羧酶/ S-腺苷甲硫氨酸脱羧酶的鸟氨酸脱羧酶结构域：两种不同构建体的重组表达及催化特性

Biochem J. 2000 Dec 1;352 Pt 2(Pt 2):287-92.

Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense.异甲脒与刚果锥虫相互作用的荧光分析。

Biochem J. 1993 May 15;292 ( Pt 1)(Pt 1):31-5. doi: 10.1042/bj2920031.

S-adenosyl-L-methionine decarboxylase of Acanthamoeba castellanii (Neff): purification and properties.卡氏棘阿米巴（内夫株）的S-腺苷-L-甲硫氨酸脱羧酶：纯化及性质

Biochem J. 1993 Oct 1;295 ( Pt 1)(Pt 1):203-9. doi: 10.1042/bj2950203.

Polyamine content and drug sensitivities of different clonal lines of Leishmania infantum promastigotes.婴儿利什曼原虫前鞭毛体不同克隆系的多胺含量与药物敏感性

Parasitol Res. 1994;80(3):203-7. doi: 10.1007/BF00932675.

Efficacy of combinations of difluoromethylornithine and bleomycin in a mouse model of central nervous system African trypanosomiasis.二氟甲基鸟氨酸与博来霉素联合用药在中枢神经系统非洲锥虫病小鼠模型中的疗效

Proc Natl Acad Sci U S A. 1983 Sep;80(18):5729-33. doi: 10.1073/pnas.80.18.5729.

Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone).布氏布氏锥虫S-腺苷-L-甲硫氨酸脱羧酶的特性及其被贝尼尔、喷他脒和甲基乙二醛双（脒腙）抑制的情况

Biochem J. 1986 Aug 1;237(3):685-9. doi: 10.1042/bj2370685.

Arginine decarboxylase inhibitors reduce the capacity of Trypanosoma cruzi to infect and multiply in mammalian host cells.精氨酸脱羧酶抑制剂降低克氏锥虫在哺乳动物宿主细胞中感染和繁殖的能力。

Proc Natl Acad Sci U S A. 1987 Jun;84(12):4278-82. doi: 10.1073/pnas.84.12.4278.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验