Jungmann E, Schulz W, Kober G, Walther F, Schöffling K
MMW Munch Med Wochenschr. 1981 Jun 5;123(23):965-8.
Though habitual, but not excessive use of laxatives can be observed frequently, no accompanying clinical symptoms have yet been described. The frequent observation of tetany and edema is striking, there is a marked decrease of potassium clearance and an incipient impairment of creatinine clearance. A secondary hyperaldosteronism can be ruled out. The electrocardiograms of 9 patients show signs of mild hypokalemia, which in 2 patients were first misinterpreted as myocardial ischemia and in one patient taken as indication of myocarditis. Oral administration of potassium normalizes the electrocardiograms.
尽管经常观察到习惯性但不过度使用泻药的情况,但尚未发现伴随的临床症状。经常观察到手足搐搦和水肿很明显,钾清除率显著降低,肌酐清除率开始受损。继发性醛固酮增多症可以排除。9例患者的心电图显示轻度低钾血症迹象,其中2例最初被误诊为心肌缺血,1例被认为是心肌炎的指征。口服钾使心电图恢复正常。