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地西泮对人体操作性行为的影响。

Effects of diazepam on operant behavior in man.

作者信息

Carlton P L, Siegel J L, Murphree H B, Cook L

出版信息

Psychopharmacology (Berl). 1981;73(4):314-7. doi: 10.1007/BF00426457.

Abstract

The effects of diazepam (10 mg orally) on the responding of normal human volunteers was studied in a procedure that involved the maintenance of operant behavior by monetary reinforcement and its suppression by monetary loss (punishment). Diazepam produced an antipunishment effect as shown by an increase in behavior suppressed by monetary loss. An analogy to animal procedures that selectively detect antianxiety drugs is apparent.

摘要

通过一种程序研究了地西泮(口服10毫克)对正常人类志愿者反应的影响,该程序包括通过金钱强化来维持操作性行为以及通过金钱损失(惩罚)来抑制该行为。地西泮产生了一种抗惩罚作用,表现为因金钱损失而被抑制的行为增加。与选择性检测抗焦虑药物的动物实验程序存在明显的相似之处。

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