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使用简单任务来测试镇静剂对复杂技能的损害。

Use of simple tasks to test for impairment of complex skills by a sedative.

作者信息

Ellinwood E H, Linnoila M, Angle H V, Moore J W, Skinner J T, Easler M, Molter D W

出版信息

Psychopharmacology (Berl). 1981;73(4):350-4. doi: 10.1007/BF00426464.

Abstract

Examination of the effect of three doses of pentobarbital on the comparative performance of a complex psychomotor task with two simple neuromotor tasks, i. e., standing steady and pendulum eye tracking, revealed a high correlation. These simple tasks could be used as measures of intoxication since they do not require extensive training. Examination of the complex task impairment blood level ratio revealed that impairment relative to blood level was much greater in the absorption phase. This changing ratio underscores the point that blood levels alone are not an adequate estimate of intoxication.

摘要

研究三种剂量的戊巴比妥对一项复杂心理运动任务与两项简单神经运动任务(即站稳和钟摆式眼球追踪)的比较表现的影响,结果显示出高度相关性。这些简单任务可作为中毒程度的衡量指标,因为它们不需要大量训练。对复杂任务损伤与血药浓度比值的研究表明,在吸收阶段,相对于血药浓度的损伤要大得多。这种变化的比值突出了仅用血药浓度不足以评估中毒程度这一点。

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