Bächi I
Acta Histochem Suppl. 1980;22:291-7.
The receptor of myxoviral hemagglutinins is defined by terminal sialic acid residues of the major sialoglycoprotein (glycophorin) of the human erythrocyte membrane. A number of lectins and antibodies are suitable to specifically label this molecule. The proposed association of glycophorin with the structures revealed as intramembrane particles (IMP) on freeze-fractured membranes rests only on indirect evidence; IMP are not composed of glycophorin alone but glycophorin may be a component of them in association with other integral membrane proteins and/or lipids. Mapping experiments employing limulin, a lectin specific for sialic acids, and anti-glycophorin are described. These experiments demonstrate a lack of association of glycophorin and the IMP.
黏液病毒血凝素的受体由人红细胞膜主要唾液酸糖蛋白（血型糖蛋白）的末端唾液酸残基所界定。许多凝集素和抗体适用于特异性标记该分子。关于血型糖蛋白与在冷冻断裂膜上显示为膜内颗粒（IMP）的结构之间的推测性关联仅基于间接证据；IMP并非仅由血型糖蛋白组成，但血型糖蛋白可能是它们与其他整合膜蛋白和/或脂质结合的一个组成部分。描述了使用鲎试剂（一种对唾液酸具有特异性的凝集素）和抗血型糖蛋白的定位实验。这些实验证明了血型糖蛋白与IMP之间缺乏关联。
