Morelli A, Benatti U, Lenzerini L, Sparatore B, Salomino F, Melloni E, Michetti M, Pontremoli S, De Flora A
Blood. 1981 Sep;58(3):642-4.
Complete removal of leukocytes and platelets from whole blood showed that the glucose-6-phosphage dehydrogenase (G6PD) activity in "pure" erythrocytes from G6PD deficient hemizygous Sardinian subjects is consistently lower than reported in the literature. Thus, although non of 27 hemizygous subjects showed undetectable erythrocyte G6PD activity, their levels ranged between 0.0015 and 0.008 IU/g Hb, as compared with a mean value of 4.5 IU/g Hb in normal subjects. Most of the biochemical peoperties that were formerly ascribed to erythrocyte G6PD appear to be those of the enzyme from contaminating leukocytes and (or) platelets.
从全血中完全去除白细胞和血小板后发现，来自葡萄糖-6-磷酸脱氢酶（G6PD）缺乏的半合子撒丁岛受试者的“纯”红细胞中的G6PD活性始终低于文献报道。因此，虽然27名半合子受试者中没有一人的红细胞G6PD活性检测不到，但他们的活性水平在0.0015至0.008 IU/g Hb之间，而正常受试者的平均值为4.5 IU/g Hb。以前归因于红细胞G6PD的大多数生化特性似乎是来自污染白细胞和（或）血小板的酶的特性。
