一个与H-2连锁的Ir基因调控对TI-2抗原DNP-菲可（DNP-Ficoll）免疫应答的证据。
Evidence for an H-2-linked Ir gene regulating the immune response to a TI-2 antigen, DNP-Ficoll.
作者信息
Schott C F, Lizzio E F, Merchant B
出版信息
J Immunogenet. 1981 Jun;8(3):235-7. doi: 10.1111/j.1744-313x.1981.tb00762.x.
Abstract
Various H-2 congenic mouse pairs were immunized with 10 microgram of DNP53-Ficoll, a thymic independent (TI-2) antigen. Four-day primary splenic immune responses were measured by a DNP-reactive PFC assay. Significantly different responses were noted between partners of many congenic pairs. An H-2 linked Ir gene for DNP-Ficoll appears likely.
摘要
用10微克二硝基苯（DNP）53 - 聚蔗糖（一种胸腺非依赖性（TI - 2）抗原）对各种H - 2同类系小鼠对进行免疫。通过DNP反应性空斑形成细胞（PFC）测定法测量4天的初次脾脏免疫反应。许多同类系对的配对伙伴之间观察到显著不同的反应。一种与H - 2连锁的针对DNP - 聚蔗糖的免疫反应基因似乎是存在的。
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