氟哌啶醇对脑电图频谱的影响。
The effects of haloperidol on the EEG spectrum.
作者信息
Wieneke G H, Verhoeven W M, Westenberg H G, de Wilde H, Lopes da Silva F H, van Praag M, Storm van Leeuwen W
出版信息
Psychopharmacology (Berl). 1981;74(1):33-4. doi: 10.1007/BF00431753.
A placebo-controlled study with six normal volunteers was carried out using 1 mg haloperidol IM. In some EEG frequency bands, the power density due to haloperidol appeared to increase or decrease depending on the subject. Nevertheless, if the results of the six subjects are taken together, the effects of haloperidol are in agreement with the literature. No correlation was found between plasma concentration of haloperidol and EEG response. Some methodological problems are discussed.
一项针对六名正常志愿者的安慰剂对照研究使用了1毫克氟哌啶醇进行肌肉注射。在某些脑电图频段中，氟哌啶醇引起的功率密度似乎因受试者而异，有的增加，有的减少。然而，如果将六名受试者的结果综合起来看，氟哌啶醇的效果与文献一致。未发现氟哌啶醇的血浆浓度与脑电图反应之间存在相关性。文中讨论了一些方法学问题。
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