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[实验性胰腺炎条件下心肌中甘油磷酸和甘油代谢的损伤]

[Impairment of glycerophosphate and glycerol turnover in myocardium under conditions of experimental pancreatitis].

作者信息

Garibian G G, Kazarian P A, Simavorian P S

出版信息

Vopr Med Khim. 1981 May-Jun;27(3):337-9.

PMID:6792779
Abstract

Initial steps of the experimental pancreatitis were characterized by an increase in glycerophosphate accumulation as well as in activity of glycerokinase, glycerophosphate dehydrogenase and glycerol dehydrogenase; content of free glycerol and dihydroacetone phosphate was also increased. Within the subsequent periods the patterns studied exhibited normalization except of glycerokinase and glycerophosphate dehydrogenase activity of which was distinctly decreased as compared with the controls.

摘要

实验性胰腺炎的初始阶段表现为甘油磷酸积累增加以及甘油激酶、甘油磷酸脱氢酶和甘油脱氢酶的活性增加;游离甘油和磷酸二羟丙酮的含量也增加。在随后的时期内,所研究的各项指标除甘油激酶和甘油磷酸脱氢酶活性外均恢复正常,与对照组相比,这两种酶的活性明显降低。

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