Frova G, Geraci P, Giurati G, Pagani I, Ronchi G
Minerva Anestesiol. 1981 May;47(5):205-14.
In 61 patients submitted to subdural anesthesia for orthopedic operations, postoperative somatic pain was treated by double-blind iv injection of lysine acetylsalicylate 1.8 g or placebo randomly. Patients with persistent pain received methadone 10 mg im. No placebo response was obtained; LAS had similar but shorter effects than methadone. No significant side effect was observed.
在61例接受硬膜下麻醉进行骨科手术的患者中,术后躯体疼痛通过随机双盲静脉注射1.8 g赖氨酸乙酰水杨酸或安慰剂进行治疗。持续性疼痛患者接受10 mg美沙酮肌肉注射。未获得安慰剂反应;赖氨酸乙酰水杨酸的效果与美沙酮相似,但作用时间较短。未观察到明显副作用。