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赖氨酸乙酰水杨酸酯用于控制躯体源性术后疼痛的双盲研究

[Double-blind study of lysine acetylsalicylate in the control of postoperative pain of somatic origin].

作者信息

Frova G, Geraci P, Giurati G, Pagani I, Ronchi G

出版信息

Minerva Anestesiol. 1981 May;47(5):205-14.

PMID:6793920
Abstract

In 61 patients submitted to subdural anesthesia for orthopedic operations, postoperative somatic pain was treated by double-blind iv injection of lysine acetylsalicylate 1.8 g or placebo randomly. Patients with persistent pain received methadone 10 mg im. No placebo response was obtained; LAS had similar but shorter effects than methadone. No significant side effect was observed.

摘要

在61例接受硬膜下麻醉进行骨科手术的患者中,术后躯体疼痛通过随机双盲静脉注射1.8 g赖氨酸乙酰水杨酸或安慰剂进行治疗。持续性疼痛患者接受10 mg美沙酮肌肉注射。未获得安慰剂反应;赖氨酸乙酰水杨酸的效果与美沙酮相似,但作用时间较短。未观察到明显副作用。

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