Andreoni A, Cristofori G B, Fochi C, Sganzerla E
Minerva Anestesiol. 1981 May;47(5):221-8.
To evaluate the action of lysine acetylsalicylate in controlling post-operative pain a controlled double blind clinical trial was carried out in thirty patients subjected to surgical procedures on the upper gastrointestinal tract. The results or the trial support analgesic properties of the drug in the postoperative period and the absence of relevant untoward effects. The low toxicity and the absence of the side effects typical to narcotic analgesics suggest to study the analgesic effects of ASL with higher dosage schedules or different administrations in order to increase the analgesic potency of the drug in the post-operative period.
为评估赖氨酸阿司匹林在控制术后疼痛方面的作用,对30例接受上消化道手术的患者进行了一项对照双盲临床试验。试验结果支持该药物在术后具有镇痛特性且无相关不良反应。其低毒性以及不存在麻醉性镇痛药典型的副作用表明,有必要研究更高剂量方案或不同给药方式的赖氨酸阿司匹林的镇痛效果,以提高该药物在术后的镇痛效力。