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[赖氨酸阿司匹林与喷他佐辛用于术后镇痛]

[Postoperative analgesia with lysine salicylate and pentazocine].

作者信息

Launo C, Molinino M, Bassi C, Carbone M, Novielli N

出版信息

Minerva Anestesiol. 1981 May;47(5):237-40.

PMID:6793924
Abstract

The analgesic effect of two doses (1.8 and 3.6 g) of acetylsalicylate of lysine and two doses (30 and 60 mg) of pentazocine was studied after random administration to 40 patients who had undergone cholecystectomy. The experimental pattern was a four-point bio-assay and pain intensity was assessed on a 0 to 100 algesimetric scale by the patients themselves upon administration of the analgesic and after 30, 60 and 120 minutes. The analgesic of acetylsalicylate of lysine proved dose-dependent with a power ratio with respect to pentazocine of between 43 and 65.

摘要

对40例接受胆囊切除术的患者随机给予赖氨酸乙酰水杨酸的两个剂量(1.8克和3.6克)以及喷他佐辛的两个剂量(30毫克和60毫克),研究其镇痛效果。实验模式为四点生物测定法,患者在服用镇痛药后以及30、60和120分钟后,根据0至100的痛觉测量量表自行评估疼痛强度。结果表明,赖氨酸乙酰水杨酸的镇痛效果呈剂量依赖性,相对于喷他佐辛的效力比在43至65之间。

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The analgesic effect of intravenous indoprofen and lysine acetylsalicylate in patients with postoperative pain.
J Clin Pharmacol. 1980 Jul;20(7):475-9. doi: 10.1002/j.1552-4604.1980.tb01721.x.

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