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一个影响家鼠肝脏中三种糖苷酶活性的基因。

A gene affecting liver activities of three glycosidases in the house mouse.

作者信息

Håkansson E M, Hilgers J, Lundin L G

出版信息

Biochem Genet. 1981 Jun;19(5-6):457-64. doi: 10.1007/BF00484618.

Abstract

A gene locus is described controlling liver activities in the house mouse of three glycosidases, i.e., beta-galactosidase, beta-glucuronidase, and N-acetyl-beta-hexosaminidase. An allele conferring low activity is present in the inbred strain LIS/A, and an allele for high activity is present in A/BrAf mice. The three enzyme activities are correlated with each other. The possible linkage between this gene and the Bgs locus on chromosome 9 is discussed.

摘要

描述了一个基因位点,它控制家鼠中三种糖苷酶的肝脏活性,即β-半乳糖苷酶、β-葡萄糖醛酸酶和N-乙酰-β-己糖胺酶。近交系LIS/A中存在一个导致低活性的等位基因,而A/BrAf小鼠中存在一个高活性等位基因。这三种酶的活性相互关联。讨论了该基因与9号染色体上Bgs位点之间可能的连锁关系。

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