肿瘤细胞因使用一种从甲基乙二醛双（胍腙）转运中刺激多胺摄取的系统而死亡。 - Suppr

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超能文献

Death of tumor cells in response to the use of a system of stimulated polyamine uptake from the transport of methylglyoxal bis(guanylhydrazone).

作者信息

Seppänen P, Alhonen-Hongisto L, Jänne J

出版信息

Eur J Biochem. 1981 Sep 1;118(3):571-6. doi: 10.1111/j.1432-1033.1981.tb05557.x.

DOI:10.1111/j.1432-1033.1981.tb05557.x

PMID:6795040

Abstract

摘要

相似文献

Death of tumor cells in response to the use of a system of stimulated polyamine uptake from the transport of methylglyoxal bis(guanylhydrazone).肿瘤细胞因使用一种从甲基乙二醛双（胍腙）转运中刺激多胺摄取的系统而死亡。

Eur J Biochem. 1981 Sep 1;118(3):571-6. doi: 10.1111/j.1432-1033.1981.tb05557.x.

Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone).细胞内腐胺和亚精胺缺乏会导致天然多胺和甲基乙二醛双（脒腙）的摄取增加。

Biochem J. 1980 Dec 15;192(3):941-5. doi: 10.1042/bj1920941.

Some properties of the polyamine deprivation-inducible uptake system for methylglyoxal bis(guanylhydrazone) in tumor cells.肿瘤细胞中甲基乙二醛双（脒腙）的多胺剥夺诱导摄取系统的一些特性。

Acta Chem Scand B. 1981;35(10):731-6. doi: 10.3891/acta.chem.scand.35b-0731.

Polyamine deprivation-induced enhanced uptake of methylglyoxal bis(guanylhydrazone) by tumor cells.多胺剥夺诱导肿瘤细胞对甲基乙二醛双（脒腙）摄取增强。

Biochim Biophys Acta. 1981 May 5;674(2):169-77. doi: 10.1016/0304-4165(81)90375-5.

Glyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in tumour cells.乙二醛双（脒腙）作为肿瘤细胞中多胺生物合成的抑制剂

Biochem J. 1984 Jul 15;221(2):483-8. doi: 10.1042/bj2210483.

Differential effect of alpha-difluoromethylornithine on the in vivo uptake of 14C-labeled polyamines and methylglyoxal bis(guanylhydrazone) by a rat prostate-derived tumor.α-二氟甲基鸟氨酸对大鼠前列腺衍生肿瘤体内摄取14C标记的多胺和甲基乙二醛双（胍腙）的差异作用。

Cancer Res. 1984 Mar;44(3):1034-40.

Modification of uptake and antiproliferative effect of methylglyoxal bis(guanylhydrazone) by treatment with alpha-difluoromethylornithine in rodent cell lines with different sensitivities to methylglyoxal bis(guanylhydrazone).用α-二氟甲基鸟氨酸处理对双胍乙腙敏感性不同的啮齿动物细胞系，对双胍乙腙摄取和抗增殖作用的影响

Cancer Res. 1985 Feb;45(2):509-14.

Increased rate of tumor cell death caused by polyamine synthesis inhibitors.多胺合成抑制剂导致肿瘤细胞死亡率增加。

Virchows Arch B Cell Pathol Incl Mol Pathol. 1984;47(2):131-8. doi: 10.1007/BF02890195.

Modulation of the tissue disposition of methylglyoxal bis(guanylhydrazone) in mice by polyamine depletion and by polyamine administration.多胺耗竭和多胺给药对小鼠中甲基乙二醛双（胍腙）组织分布的调节作用。

Cancer Res. 1983 Jan;43(1):324-7.

Different efflux rates may determine the cellular accumulation of various bis(guanylhydrazones).不同的外排速率可能决定了各种双（胍腙）的细胞蓄积。

Biochem J. 1984 Jul 1;221(1):273-6. doi: 10.1042/bj2210273.

引用本文的文献

Glyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in tumour cells.乙二醛双（脒腙）作为肿瘤细胞中多胺生物合成的抑制剂

Biochem J. 1984 Jul 15;221(2):483-8. doi: 10.1042/bj2210483.

Differential effects of 2-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) on the testosterone-induced growth of ventral prostate and seminal vesicles of castrated rats.2-二氟甲基鸟氨酸和甲基乙二醛双（脒腙）对去势大鼠睾酮诱导的前列腺腹侧叶和精囊生长的不同作用。

Biochem J. 1984 May 1;219(3):811-7. doi: 10.1042/bj2190811.

Transfer of intestine-derived diamines into tumour cells during treatment of Ehrlich-ascites--carcinoma-bearing mice with polyamine anti-metabolites.在用多胺抗代谢物治疗艾氏腹水癌荷瘤小鼠过程中，肠道来源的二胺向肿瘤细胞的转移。

Biochem J. 1984 Mar 1;218(2):641-4. doi: 10.1042/bj2180641.

Role of diamine oxidase during the treatment of tumour-bearing mice with combinations of polyamine anti-metabolites.二胺氧化酶在荷瘤小鼠用多胺抗代谢物组合治疗过程中的作用

Biochem J. 1983 Jun 15;212(3):895-8. doi: 10.1042/bj2120895.

Phase I evaluation of intravenous difluoromethylornithine--a polyamine inhibitor.静脉注射二氟甲基鸟氨酸（一种多胺抑制剂）的I期评估

Invest New Drugs. 1985;3(3):287-92. doi: 10.1007/BF00179433.

Alterations in human circulating and bone marrow mononuclear cell polyamine levels in hematologic malignancies as a consequence of difluoromethylornithine administration.由于给予二氟甲基鸟氨酸导致血液系统恶性肿瘤患者循环和骨髓单个核细胞多胺水平的改变。

Invest New Drugs. 1988 Jun;6(2):125-34. doi: 10.1007/BF00195371.

Mechanisms of asbestos-induced squamous metaplasia in tracheobronchial epithelial cells.石棉诱导气管支气管上皮细胞鳞状化生的机制。

Environ Health Perspect. 1989 Mar;80:101-8. doi: 10.1289/ehp.8980101.

Expression of a human gene for polyamine transport in Chinese-hamster ovary cells.人多胺转运基因在中国仓鼠卵巢细胞中的表达。

Biochem J. 1989 Nov 1;263(3):745-52. doi: 10.1042/bj2630745.

Mononuclear cell polyamine content associated with myeloid maturation in patients with leukemia during administration of polyamine inhibitors.白血病患者在使用多胺抑制剂期间，与髓系成熟相关的单核细胞多胺含量。

Invest New Drugs. 1989 Jul;7(2-3):119-29. doi: 10.1007/BF00170848.

Role of unsaturated derivatives of spermidine as substrates for spermine synthase and in supporting growth of SV-3T3 cells.亚精胺的不饱和衍生物作为精胺合酶底物及支持SV - 3T3细胞生长的作用。

Biochem J. 1991 Feb 15;274 ( Pt 1)(Pt 1):167-71. doi: 10.1042/bj2740167.

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