Weppelman R M, Tolman R L, Van Iderstine A A, Peterson L, Olson G
Experientia. 1981;37(9):995-7. doi: 10.1007/BF01971800.
Clonidine was anovulatory and markedly antigonadal in laying hens when infused for 1 week from minipump implants at daily rates of 1.08 mg per hen or greater. The ovaries of hens treated with clonidine responded to FSH injections which suggests that the antigonadal effect of clonidine resulted from a reduction in the output of gonadotropin by the pituitary. These data suggest that alpha 2 receptors may be important in regulating avian fertility.
当以每只母鸡每天1.08毫克或更高的剂量通过微型泵植入物连续输注1周时,可乐定对产蛋母鸡无排卵作用且具有明显的抗性腺作用。用可乐定处理的母鸡的卵巢对促卵泡激素注射有反应,这表明可乐定的抗性腺作用是由于垂体促性腺激素分泌减少所致。这些数据表明α2受体可能在调节禽类繁殖力方面很重要。