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[源自N-苯甲酰基氨基酸的手性烷基铵盐对大肠杆菌和蜡状芽孢杆菌的杀菌活性评估。I.——抗菌活性评估(作者译)]

[Evaluation of the bactericidal activity of chiral alkylammonium salts derived from N-benzoyl-amino acids with Escherichia coli and Bacillus cereus. I. -- Evaluation of the antibacterial activity (author's transl)].

作者信息

Massé J, Thévenard B

出版信息

Pathol Biol (Paris). 1981 Oct;29(8):468-72.

PMID:6795576
Abstract

Long-chained alkylammonium salts (C12 and C16) obtained from chiral N-benzoyl-amino acids were tested against Escherichia coli and Bacillus cereus, to evaluate their antibacterial efficacy. The bactericidal activity (MBC) determined by the membrane filtration technique and the bacteriostatic activity values suggested anionic group participation. The participation of the anion moiety, depended on nature and configuration of the amino acid. Stereoselective interactions appeared between bacteria and the cationic surfactants tested.

摘要

对手性N-苯甲酰基氨基酸制得的长链烷基铵盐(C12和C16)进行了抗大肠杆菌和蜡样芽孢杆菌测试,以评估其抗菌效果。通过膜过滤技术测定的杀菌活性(MBC)和抑菌活性值表明有阴离子基团参与。阴离子部分的参与取决于氨基酸的性质和构型。在细菌与所测试的阳离子表面活性剂之间出现了立体选择性相互作用。

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