Massé J, Thévenard B
Pathol Biol (Paris). 1981 Oct;29(8):473-80.
By testing the antibacterial activity of new long-chained alkylammonium salts with organic asymmetric anions (N-benzoyl-amino-acids) we have been able to precise the kind of interaction that would take place between the microorganisms and the two groups of the surfactant molecule. Evidence for anion participation to the bactericidal activity appeared through kind and configuration of the amino acid. A mechanism is proposed, that takes into account, hydrophobic and ionic interactions with cation and anion participation.
通过测试带有有机不对称阴离子(N-苯甲酰基氨基酸)的新型长链烷基铵盐的抗菌活性,我们得以明确微生物与表面活性剂分子的两组基团之间会发生何种相互作用。氨基酸的种类和构型显示出阴离子参与杀菌活性的证据。我们提出了一种机制,该机制考虑了与阳离子的疏水和离子相互作用以及阴离子的参与。