UK-37,248，一种新型的选择性血栓素合成酶抑制剂，具有血小板抗聚集和抗血栓形成活性。 - Suppr

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UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity.

作者信息

Randall M J, Parry M J, Hawkeswood E, Cross P E, Dickinson R P

出版信息

Thromb Res. 1981;23(1-2):145-62. doi: 10.1016/0049-3848(81)90247-4.

DOI:10.1016/0049-3848(81)90247-4

PMID:6795753

Abstract

摘要

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UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity.UK-37,248，一种新型的选择性血栓素合成酶抑制剂，具有血小板抗聚集和抗血栓形成活性。

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Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity.血栓素合成酶抑制剂UK-37,248（达唑氧苯）对血小板聚集、冠状动脉血栓形成及血管反应性的影响。

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Effects of Y-20811, a long-lasting thromboxane synthetase inhibitor, on thromboxane production and platelet function.长效血栓素合成酶抑制剂Y-20811对血栓素生成及血小板功能的影响。

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Lag-phase of arachidonic acid-induced secretion in responders and non-responders to the thromboxane-synthetase inhibitors: involvement of cyclic-AMP.对血栓素合成酶抑制剂有反应者和无反应者中花生四烯酸诱导分泌的延迟期：环磷酸腺苷的作用。

Thromb Res. 1984 Jul 1;35(1):91-7. doi: 10.1016/0049-3848(84)90316-5.

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Br J Clin Pharmacol. 1983;15 Suppl 1(Suppl 1):49S-55S. doi: 10.1111/j.1365-2125.1983.tb02107.x.

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