碳酸锂治疗“开-关”综合征：一例报告
"On-off" syndrome treated with lithium carbonate: a case report.
作者信息
Ross D R, Coffey C E, Ferren E L, Walker J I, Olanow C W
出版信息
Am J Psychiatry. 1981 Dec;138(12):1626-7. doi: 10.1176/ajp.138.12.1626.
PMID:6795945
Abstract
The authors describe a 42-year-old man who developed "on-off" episodes and for whom lithium carbonate proved an effective treatment. They speculate that the predominant effect of lithium in the "on-off" syndrome is to prevent L-dopa desensitization of the dopamine receptor.
摘要
作者描述了一名42岁的男性，他出现了“开-关”现象，而碳酸锂被证明是一种有效的治疗方法。他们推测，锂在“开-关”综合征中的主要作用是防止多巴胺受体对左旋多巴产生脱敏。
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