皮质类固醇对己巴比妥和甲苯磺丁脲处置的影响。
Influence of corticosteroid on hexobarbital and tolbutamide disposition.
作者信息
Breimer D D, Zilly W, Richter E
出版信息
Clin Pharmacol Ther. 1978 Aug;24(2):208-12. doi: 10.1002/cpt1978242208.
PMID:679598
Abstract
The influence of 10 days' prednisone treatment on the disposition of hexobarbital and tolbutamide was studied in 7 healthy male volunteers. No significant changes in the pharmacokinetic parameters of the two drugs became apparent, which indicates that prednisone pretreatment does not affect their metabolic activities.
摘要
在7名健康男性志愿者中研究了10天泼尼松治疗对己巴比妥和甲苯磺丁脲处置的影响。两种药物的药代动力学参数未出现明显变化，这表明泼尼松预处理不影响它们的代谢活性。
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