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1-Chloro-2,2,2-trifluoroethyl radical: Formation from halothane by human cytochrome P-450 in reconstituted vesicles and binding to phospholipids.

作者信息

Trudell J R, Trevor A

出版信息

Biochem Biophys Res Commun. 1981 Sep 16;102(1):372-7. doi: 10.1016/0006-291x(81)91531-x.

DOI:10.1016/0006-291x(81)91531-x
PMID:6796087
Abstract
摘要

相似文献

1
1-Chloro-2,2,2-trifluoroethyl radical: Formation from halothane by human cytochrome P-450 in reconstituted vesicles and binding to phospholipids.1-氯-2,2,2-三氟乙基自由基：在重组囊泡中由人细胞色素P-450催化氟烷生成并与磷脂结合。
Biochem Biophys Res Commun. 1981 Sep 16;102(1):372-7. doi: 10.1016/0006-291x(81)91531-x.
2
Anaerobic dehalogenation of halothane by reconstituted liver microsomal cytochrome P-450 enzyme system.
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3
Isoflurane acts as an inhibitor of oxidative dehalogenation while acting as an accelerator of reductive dehalogenation of halothane in guinea pig liver microsomes.
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4
Reductive metabolism of halothane by human and rabbit cytochrome P-450. Binding of 1-chloro-2,2,2-trifluoroethyl radical to phospholipids.氟烷在人和兔细胞色素P-450作用下的还原代谢。1-氯-2,2,2-三氟乙基自由基与磷脂的结合。
Mol Pharmacol. 1982 May;21(3):710-7.
5
Cytochrome b5 as electron donor to rabbit liver cytochrome P-450LM2 in reconstituted phospholipid vesicles.细胞色素b5作为电子供体在重组磷脂囊泡中作用于兔肝细胞色素P - 450LM2。
Biochem Biophys Res Commun. 1980 Nov 28;97(2):582-6. doi: 10.1016/0006-291x(80)90303-4.
6
[Dynamics of protein-protein interaction in a monoxygenase enzyme system reconstructed in liposomes of various phospholipid composition].
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7
A spin trap study on anaerobic dehalogenation of halothane by a reconstituted liver microsomal cytochrome P-450 enzyme system.
J Biochem. 1982 Jan;91(1):415-8. doi: 10.1093/oxfordjournals.jbchem.a133704.
8
The association of cytochrome P-450 and NADPH-cytochrome P-450 reductase in phospholipid membranes.细胞色素P-450与NADPH-细胞色素P-450还原酶在磷脂膜中的关联。
Arch Biochem Biophys. 1984 Oct;234(1):161-6. doi: 10.1016/0003-9861(84)90337-0.
9
Incorporation of purified components of the rabbit liver microsomal hydroxylase system into phospholipid vesicles.将兔肝微粒体羟化酶系统的纯化组分掺入磷脂囊泡中。
Biochim Biophys Acta. 1980 Jul;599(2):417-35. doi: 10.1016/0005-2736(80)90188-1.
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Possible association of NADPH-cytochrome P-450 reductase and cytochrome P-450 in reconstituted phospholipid vesicles.还原型辅酶Ⅱ-细胞色素P-450还原酶与细胞色素P-450在重构磷脂囊泡中的可能关联。
Biochemistry. 1983 Jul 19;22(15):3586-94. doi: 10.1021/bi00284a008.

引用本文的文献

1
Modification of liver microsomal lipids by halothane metabolites; a multi nuclear NMR spectroscopic study.氟烷代谢产物对肝脏微粒体脂质的修饰；一项多核核磁共振光谱研究。
Naunyn Schmiedebergs Arch Pharmacol. 1982 Dec;321(3):234-7. doi: 10.1007/BF00505492.
2
Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine.在磷脂囊泡中重组的人细胞色素P-450对四氯化碳的还原代谢：与二油酰磷脂酰胆碱结合的三氯甲基自由基的质谱鉴定
Proc Natl Acad Sci U S A. 1982 Apr;79(8):2678-82. doi: 10.1073/pnas.79.8.2678.
3
Biochemical studies on the metabolic activation of halogenated alkanes.
卤代烷烃代谢活化的生化研究。
Environ Health Perspect. 1985 Dec;64:85-101. doi: 10.1289/ehp.856485.
4
Model studies in cytochrome P-450-mediated toxicity of halogenated compounds: radical processes involving iron porphyrins.细胞色素P-450介导的卤代化合物毒性的模型研究：涉及铁卟啉的自由基过程。
Environ Health Perspect. 1985 Dec;64:53-60. doi: 10.1289/ehp.856453.
5
Chemistry and biology of spin-trapping radicals associated with halocarbon metabolism in vitro and in vivo.体外和体内与卤代烃代谢相关的自旋捕获自由基的化学与生物学特性
Environ Health Perspect. 1985 Dec;64:151-70. doi: 10.1289/ehp.8564151.
6
Saturable binding of halothane to rat brain synaptosomes.氟烷与大鼠脑突触体的饱和结合
Proc Natl Acad Sci U S A. 1992 May 15;89(10):4329-32. doi: 10.1073/pnas.89.10.4329.