Shinkawa O, Furuhashi N, Fukaya T, Kono H, Tachibana Y, Suzuki M
Nihon Sanka Fujinka Gakkai Zasshi. 1981 Oct;33(10):1635-8.
We measured FSH and LH concentrations in 130 cord sera and 217 peripheral sera obtained from infants of 28-42 weeks in gestation, aged 5-75 days after birth, by radioimmunoassay. Cord FSH and LH levels were 3.9-13.6 mIU/ml and 43.3-88.5 mIU/ml respectively, and decreased with advancing gestation. Although FSH levels in 28-31 weeks were higher in female than in male, another sex difference was not found. Postnatal FSH levels in male preterm infants decreased within 10 day, thereafter continued low levels (3.7-5.6 mIU/ml). However, in male term infants and female infants, FSH levels increased with peak levels between 11-30 days after birth, and then decreased gradually. The elevation of FSH levels in female was more remarked and prolonged in preterm infants than in term infants. Postnatal LH levels in both male and female decreased rapidly after birth, and then had similar pattern of FSH levels. Serum gonadotropin levels during the neonatal period were higher in female than in male, except for LH in term infants (male greater than female).
我们采用放射免疫分析法，检测了130份脐带血清和217份外周血清中的促卵泡激素（FSH）和促黄体生成素（LH）浓度，这些样本来自妊娠28 - 42周、出生后5 - 75天的婴儿。脐带FSH和LH水平分别为3.9 - 13.6 mIU/ml和43.3 - 88.5 mIU/ml，并随孕周增加而降低。虽然在28 - 31周时，女性的FSH水平高于男性，但未发现其他性别差异。男性早产儿出生后10天内FSH水平下降，此后持续处于低水平（3.7 - 5.6 mIU/ml）。然而，男性足月儿和女性婴儿出生后FSH水平升高，在出生后11 - 30天达到峰值，然后逐渐下降。女性FSH水平的升高在早产儿中比足月儿更显著且持续时间更长。出生后男性和女性的LH水平均迅速下降，然后呈现与FSH水平相似的模式。除足月儿的LH水平（男性高于女性）外，新生儿期女性的血清促性腺激素水平高于男性。
