危重症患者的游离甲状腺素水平。现有检测方法的比较。
Free thyroxine levels in critically ill patients. A comparison of currently available assays.
作者信息
Slag M F, Morley J E, Elson M K, Labrosse K R, Crowson T W, Nuttall F Q, Shafer R B
出版信息
JAMA. 1981 Dec 11;246(23):2702-6.
Two indices of free thyroxine (T4) and four methods of free T4 measurement were compared in 85 patients with acute illness, hospitalized in intensive care units. All of the methods of free T4 measurement in critical illness were nonspecific, and two of the methods failed to suggest hypothyroidism in two patients with primary hypothyroidism and another associated critical illness. Since the ideal screening test should be both sensitive and specific, all tests for free T4 used in this study should be interpreted with caution in severely ill patients.
在85例入住重症监护病房的急性病患者中，对两种游离甲状腺素（T4）指标和四种游离T4测量方法进行了比较。危重病中所有游离T4测量方法均缺乏特异性，其中两种方法未能在两名原发性甲状腺功能减退症合并其他危重病的患者中提示甲状腺功能减退。由于理想的筛查试验应兼具敏感性和特异性，因此本研究中使用的所有游离T4检测在重症患者中均应谨慎解读。
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