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II型高胆固醇血症：门腔分流术后血浆胰岛素和胰高血糖素水平的变化

Hypercholesterolaemia type II: changes in plasma insulin and glucagon levels after portacaval shunt.

作者信息

Farriaux J P, Luyckx A S, Ribet M

出版信息

J Inherit Metab Dis. 1980;2(3):55-8. doi: 10.1007/BF01801719.

DOI:10.1007/BF01801719
PMID:6796760
Abstract

Insulinaemia and glucagonaemia were measured in two cases of hypercholesterolaemia type II, before and after portacaval shunt. The results show an increase of both hormones although these variations are not concomitant with the decrease in cholesterolaemia. The data still do not explain the mechanism of the decrease.

摘要

在两例II型高胆固醇血症患者中，于门腔分流术前及术后测定了胰岛素血症和胰高血糖素血症。结果显示两种激素均升高，尽管这些变化与胆固醇血症的降低并不同步。这些数据仍无法解释胆固醇血症降低的机制。

相似文献

1
Hypercholesterolaemia type II: changes in plasma insulin and glucagon levels after portacaval shunt.II型高胆固醇血症：门腔分流术后血浆胰岛素和胰高血糖素水平的变化
J Inherit Metab Dis. 1980;2(3):55-8. doi: 10.1007/BF01801719.
2
Portacaval shunt in familial hypercholesterolaemia.家族性高胆固醇血症中的门腔分流术。
Lancet. 1983 Jan 22;1(8317):193. doi: 10.1016/s0140-6736(83)92802-7.
3
How rapidly do hyperinsulinaemia and hyperglucagonaemia develop after portacaval shunting?门腔分流术后高胰岛素血症和高胰高血糖素血症发展得有多快？
J Surg Res. 1992 Jul;53(1):20-3. doi: 10.1016/0022-4804(92)90007-m.
4
Treatment of homozygous familial hypercholesterolaemia.纯合子家族性高胆固醇血症的治疗。
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Portacaval diversion for severe hypercholesterolemia. Report of a case with measurements of glucose tolerance, insulin, and glucagon levels.门腔分流术治疗重度高胆固醇血症。一例伴有葡萄糖耐量、胰岛素及胰高血糖素水平测定的病例报告。
Arch Surg. 1977 May;112(5):634-6. doi: 10.1001/archsurg.1977.01370050094016.
6
Serum lipids, insulin, and glucagon after portacaval shunt in cirrhosis.
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Surg Gynecol Obstet. 1981 Feb;152(2):187-90.
8
[Portacaval anastomosis in 2 cases of homozygote familial hypercholesterolemia].[2例纯合子家族性高胆固醇血症的门腔静脉吻合术]
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Response of extrapancreatic glucagon to glycemic changes.胰腺外胰高血糖素对血糖变化的反应。
Endocrinol Jpn. 1980 Dec;27 Suppl 1:121-6. doi: 10.1507/endocrj1954.27.supplement_121.
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Treatment of homozygous familial hypercholesterolaemia with portacaval shunt.门腔分流术治疗纯合子家族性高胆固醇血症
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本文引用的文献

1
The influence of portal blood upon lipid metabolism in normal and diabetic dogs and baboons.门静脉血对正常及糖尿病犬和狒狒脂质代谢的影响。
Surg Gynecol Obstet. 1975 Mar;140(3):381- 96.
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Effects of glucagon on plasma lipids in different types of primary hyperlipoproteinemia.胰高血糖素对不同类型原发性高脂蛋白血症患者血脂的影响。
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Effect of intraduodenal glucose administration on hepatic extraction of insulin in the anesthetized dog.十二指肠内给予葡萄糖对麻醉犬肝脏胰岛素摄取的影响。
J Clin Invest. 1973 Aug;52(8):2016-28. doi: 10.1172/JCI107386.
4
[Effect of glucagon on cholesterol esterification and on blood cholesterol levels in normal and hyperlipidemic subjects].[胰高血糖素对正常和高脂血症患者胆固醇酯化及血胆固醇水平的影响]
Union Med Can. 1973 Apr;102(4):876-83.
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Homozygous hypercholesteraemia and the portacaval shunt. The need for a concerted attack by surgeons and clinical researchers.
Lancet. 1974 Aug 24;2(7878):449-51. doi: 10.1016/s0140-6736(74)91828-5.
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Portacaval shunt in hyperlipoproteinaemia.
Lancet. 1973 Oct 27;2(7835):940-4. doi: 10.1016/s0140-6736(73)92599-3.
7
The effect of selective visceral caval shunt on plasma lipids and cholesterol dynamics.选择性腔静脉分流术对血脂及胆固醇动态变化的影响。
Surgery. 1977 Jul;82(1):42-50.
8
The role of the liver in glucagon metabolism.肝脏在胰高血糖素代谢中的作用。
J Clin Invest. 1977 Aug;60(2):421-8. doi: 10.1172/JCI108791.
9
Portacaval diversion for severe hypercholesterolemia. Report of a case with measurements of glucose tolerance, insulin, and glucagon levels.门腔分流术治疗重度高胆固醇血症。一例伴有葡萄糖耐量、胰岛素及胰高血糖素水平测定的病例报告。
Arch Surg. 1977 May;112(5):634-6. doi: 10.1001/archsurg.1977.01370050094016.
10
Growth hormone, glucagon, and insulin response to depression of plasma free fatty acids and the effect of glucose infusion.生长激素、胰高血糖素以及胰岛素对血浆游离脂肪酸降低的反应及葡萄糖输注的影响。
J Clin Endocrinol Metab. 1977 Feb;44(2):383-91. doi: 10.1210/jcem-44-2-383.