Weglicki W B, Ganda O P, Soeldner J S, Murawski B J, Cohn L H, Couch N P
Arch Surg. 1977 May;112(5):634-6. doi: 10.1001/archsurg.1977.01370050094016.
An end-to-side portacaval shunt was performed in a patient with severe coronary arteriosclerosis and type IIa hypercholesterolemia. By one year postoperatively there was a decrease of serum cholesterol concentration of more than 40%. No adverse side effects were noted. Intravenous and oral glucose tolerance tests were performed and were within normal range preoperatively and postoperatively. However, preoperatively, during the oral test, the serum insulin levels exceeded the normal range. In addition, glucagon levels revealed less tendency to suppression during the preoperative oral tests. Psychological testing revealed no abnormalitites, and serum ammonia levels were only slightly elevated.
对一名患有严重冠状动脉硬化和IIa型高胆固醇血症的患者进行了端侧门腔分流术。术后一年，血清胆固醇浓度下降超过40%。未观察到不良副作用。进行了静脉和口服葡萄糖耐量试验，术前和术后均在正常范围内。然而，术前口服试验期间，血清胰岛素水平超过正常范围。此外，术前口服试验期间胰高血糖素水平显示出较少的抑制趋势。心理测试未发现异常，血清氨水平仅略有升高。
