Khan O, Ell P J, Jarritt P H, Cullum I D, Williams E S
Br Med J (Clin Res Ed). 1981 Nov 7;283(6301):1212-4. doi: 10.1136/bmj.283.6301.1212.
Emission computed tomography (emission CT) and conventional planar gamma-camera imaging of the liver were compared in 242 patients with suspected metastatic spread to liver. Concordant data were obtained in 171 patients (71%). Single large lesions, multiple small lesions, and diffuse disease were accurately defined with this new radionuclide tomographic technique. The smallest lesion detected by emission CT was 8 mm. Emission CT, planar gamma-camera imaging, and transmission (x-ray) CT were compared in 107 patients. All three methods gave identical results in 76 patients (71%). Assessed against other criteria, such as histological findings and follow-up data, emission CT yielded the highest range of accuracy (92-96%), while transmission CT and planar gamma-camera imaging had similar but lower accuracies (78-81%). Emission CT had a false-positive rate of 2.8% and a false-negative rate of less than 1%. Thus emission CT is highly sensitive in detecting space-occupying disease in the liver.
对242例疑似肝转移扩散的患者进行了发射型计算机断层扫描（发射型CT）与传统肝脏平面γ相机成像的比较。171例患者（71%）获得了一致的数据。采用这种新的放射性核素断层扫描技术可准确界定单个大病灶、多个小病灶及弥漫性病变。发射型CT检测到的最小病灶为8毫米。对107例患者进行了发射型CT、平面γ相机成像及透射（X线）CT的比较。76例患者（71%）的三种方法结果相同。根据组织学检查结果及随访数据等其他标准评估，发射型CT的准确率最高（92% - 96%），而透射型CT和平面γ相机成像的准确率相似但较低（78% - 81%）。发射型CT的假阳性率为2.8%，假阴性率小于1%。因此，发射型CT在检测肝脏占位性病变方面高度敏感。
