Ell P J, Deacon J M, Ducassou D, Brendel A
Br Med J. 1980 Feb 16;280(6212):438-40. doi: 10.1136/bmj.280.6212.438.
Comparative emission and transmission brain tomograms were obtained in 209 patients to establish the diagnostic accuracy of a new emission tomographic scanner in detecting space-occupying disease in the brain. Concordant results were obtained in 169 patients (81%). Computed transmission tomography (transmission CT) yielded an overall rate of false-positive results of 0.48% and a false-negative rate of 6%. Emission CT yielded a false-positive rate of 0% and false-negative rates of 2.4% for malignant disease and 10% for vascular disease. The higher rate of false-negative results for vascular disease with emission CT occurs because transmission CT can detect old infarction. The rates of detection of recent vascular disease with emission and trnasmission CT are identical. Thus emission CT is highly sensitive in detecting space-occupying disease in the brain. It represents an ideal screening procedure.
对209例患者进行了发射型和透射型脑断层扫描，以确定一种新型发射型断层扫描仪检测脑部占位性病变的诊断准确性。169例患者（81%）得到了一致的结果。计算机透射断层扫描（透射CT）的假阳性结果总发生率为0.48%，假阴性率为6%。发射型CT的假阳性率为0%，恶性疾病的假阴性率为2.4%，血管疾病的假阴性率为10%。发射型CT对血管疾病的假阴性结果发生率较高，是因为透射CT可以检测陈旧性梗死。发射型CT和透射CT对近期血管疾病的检测率相同。因此，发射型CT在检测脑部占位性病变方面具有高度敏感性。它是一种理想的筛查方法。
