博来霉素与放射疗法同时用于头颈部恶性肿瘤的治疗。

Simultaneous use of bleomycin and radiotherapy in malignant tumours of the head and neck.

作者信息

De-la-Garza J G, García Olivares F, Armendariz C, Flores-F A M

出版信息

J Int Med Res. 1976;4(3):158-64. doi: 10.1177/030006057600400303.

Abstract

Twenty cases originally diagnosed as epidermoid carcinoma were observed with a view to determining whether a combination of radiation and intravenous bleomycin promoted regression of the tumours and if so what effect this had on survival. Signs of local toxicity with this combination were also looked for. Five cases yielded what was considered to be an excellent response, nine cases gave a good response and six cases had a poor response. It is recommended that future studies be carried out in epidermoid carcinoma with this combination of radiotherapy and bleomycin.

摘要

对最初诊断为表皮样癌的20例患者进行了观察，以确定放疗与静脉注射博来霉素联合使用是否能促进肿瘤消退，若能促进消退，那么对生存率有何影响。同时也探寻了该联合治疗产生局部毒性的迹象。5例患者有极佳反应，9例患者反应良好，6例患者反应不佳。建议今后对表皮样癌采用放疗与博来霉素联合治疗进行研究。