控制小鼠对鼠白血病病毒抗性的Fv-4小鼠基因的定位
Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses.
作者信息
Ikeda H, Sato H, Odaka T
出版信息
Int J Cancer. 1981 Aug 15;28(2):237-40. doi: 10.1002/ijc.2910280218.
PMID:6797957
Abstract
Fv-4, a gene controlling susceptibility to ecotropic murine leukemia viruses, was linked to both Pre-I (prealbumin) and Igh-I (immunoglobulin heavy-chain constant region) loci on chromosome 12 in mice. The gene order was Fv-4 - Pre-I - Igh-I, and the estimated frequency of recombination between Fv-4 and Pre-I was about 20%.
摘要
Fv-4是一种控制对亲嗜性鼠白血病病毒易感性的基因，它与小鼠12号染色体上的前白蛋白（Pre-I）和免疫球蛋白重链恒定区（Igh-I）基因座均相关联。基因顺序为Fv-4 - Pre-I - Igh-I，Fv-4与Pre-I之间的重组估计频率约为20%。
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