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口腔癌与芳烃羟化酶诱导性、吸烟及牙齿状况的关系

Carcinoma of the oral cavity in relation to aryl hydrocarbon hydroxylase inducibility, smoking and dental status.

作者信息

Trell E, Björlin G, Andréasson L, Korsgaard R, Mattiasson I

出版信息

Int J Oral Surg. 1981 Apr;10(2):93-9. doi: 10.1016/s0300-9785(81)80018-x.

DOI:10.1016/s0300-9785(81)80018-x
PMID:6797967
Abstract

The authors investigated the smoking patterns in a consecutive series of 20 patients with oral cancer and at the same time assessed the aryl hydrocarbon hydroxylase (AHH) inducibility distribution and dental status. The AHH level proved high in 8 patients, intermediate in 7 and low in 5. High AHH inducibility was more common (p = less than 0.001) and low AHH inducibility less common (p = less than 0.001) than in the controls. Dental status was poor in only 2 patients. It is concluded that smoking is a prominent exogenous factor associated with the occurrence of cancer in the oral cavity. Poor dental status seems to be of minor importance.

摘要

作者对连续的20例口腔癌患者的吸烟模式进行了调查,同时评估了芳烃羟化酶(AHH)诱导性分布和牙齿状况。结果显示,8例患者的AHH水平较高,7例中等,5例较低。与对照组相比,高AHH诱导性更为常见(p<0.001),低AHH诱导性则较少见(p<0.001)。只有2例患者的牙齿状况较差。研究得出结论,吸烟是与口腔癌发生相关的一个突出的外源性因素。牙齿状况差似乎不太重要。

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引用本文的文献

1
Leucoplakia of the oral cavity, smoking and arylhydrocarbon-hydroxylase inducibility.口腔白斑、吸烟与芳烃羟化酶诱导性
Postgrad Med J. 1982 Mar;58(677):138-41. doi: 10.1136/pgmj.58.677.138.
2
Aryl hydrocarbon hydroxylase induction levels in patients with malignant tumors associated with smoking.与吸烟相关的恶性肿瘤患者中芳烃羟化酶的诱导水平。
J Cancer Res Clin Oncol. 1984;108(3):286-9. doi: 10.1007/BF00390459.