口腔癌与芳烃羟化酶诱导性、吸烟及牙齿状况的关系

Carcinoma of the oral cavity in relation to aryl hydrocarbon hydroxylase inducibility, smoking and dental status.

作者信息

Trell E, Björlin G, Andréasson L, Korsgaard R, Mattiasson I

出版信息

Int J Oral Surg. 1981 Apr;10(2):93-9. doi: 10.1016/s0300-9785(81)80018-x.

Abstract

The authors investigated the smoking patterns in a consecutive series of 20 patients with oral cancer and at the same time assessed the aryl hydrocarbon hydroxylase (AHH) inducibility distribution and dental status. The AHH level proved high in 8 patients, intermediate in 7 and low in 5. High AHH inducibility was more common (p = less than 0.001) and low AHH inducibility less common (p = less than 0.001) than in the controls. Dental status was poor in only 2 patients. It is concluded that smoking is a prominent exogenous factor associated with the occurrence of cancer in the oral cavity. Poor dental status seems to be of minor importance.

摘要

作者对连续的20例口腔癌患者的吸烟模式进行了调查，同时评估了芳烃羟化酶（AHH）诱导性分布和牙齿状况。结果显示，8例患者的AHH水平较高，7例中等，5例较低。与对照组相比，高AHH诱导性更为常见（p＜0.001），低AHH诱导性则较少见（p＜0.001）。只有2例患者的牙齿状况较差。研究得出结论，吸烟是与口腔癌发生相关的一个突出的外源性因素。牙齿状况差似乎不太重要。