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Megakaryocytic leukemia; identification utilizing anti-factor VIII immunoperoxidase.

作者信息

Innes D J, Mills S E, Walker G K

出版信息

Am J Clin Pathol. 1982 Jan;77(1):107-10. doi: 10.1093/ajcp/77.1.107.

DOI:10.1093/ajcp/77.1.107
PMID:6798857
Abstract

Coagulation Factor VIII is produced by endothelial cells and megakaryocytes. Antibody directed against Factor VIII or its associated antigens has been shown to be a sensitive marker for both normal and neoplastic endothelial cells. Its use to identify neoplastic megakaryocytes has not been described. We used immunoperoxidase localization of Factor VIII to identify megakaryocytes and immature megakaryocytic precursors in a case of megakaryocytic leukemia.

摘要

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引用本文的文献

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J Clin Pathol. 1985 Aug;38(8):849-54. doi: 10.1136/jcp.38.8.849.
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J Clin Pathol. 1987 Aug;40(8):870-3. doi: 10.1136/jcp.40.8.870.
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