Bentue-Ferrer D, Allain H, Reymann J M, Van den Driessche J
Toxicol Eur Res. 1981 Nov;3(6):279-83.
The authors studied the neuro endocrinological effects of three pesticides. Two of them were organophosphorus compounds (ethyl parathion and dimethoate) and one was a carbamate (zineb). Mature female rats have been orally administered these compounds for 16 days at respectively 1/25, 1/10 and 1/10 of the LD50. The parameters recorded are: the gonadotropins, the length of estrous cycle and the weight of the anterior pituitary gland, the ovaries and the uterus. In contradistinction with the organochlorine compounds the organophosphorus did not induce any disturbances in the neuro endocrinological system, whereas the carbamate compound decreased the pituitary gonadotropins.
作者研究了三种农药的神经内分泌效应。其中两种是有机磷化合物（对硫磷和乐果），一种是氨基甲酸盐（代森锌）。已对成年雌性大鼠分别以半数致死剂量（LD50）的1/25、1/10和1/10口服给予这些化合物16天。记录的参数包括：促性腺激素、发情周期长度以及垂体前叶、卵巢和子宫的重量。与有机氯化合物不同，有机磷化合物未引起神经内分泌系统的任何紊乱，而氨基甲酸盐化合物则降低了垂体促性腺激素。
