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恶性眼内肿瘤

Malignant intraocular tumors.

作者信息

Brady L W, Shields J A, Augsburger J J, Day J L

出版信息

Cancer. 1982 Feb 1;49(3):578-85. doi: 10.1002/1097-0142(19820201)49:3<578::aid-cncr2820490330>3.0.co;2-a.

Abstract

The role of the radiation therapist in the management of malignant intraocular tumors is changing. With more active identification of malignant intraocular tumors, and a better recognization of the manner in which one can deal with problems of radiation sensitivity, radiation techniques of all sorts will be more actively employed in the treatment of these tumors. Special techniques must be selected for appropriate circumstances of management in order to diminish to an absolute minimum the impact upon the lens, the impact upon visual acuity and the impact upon the cornea. Cobalt-60 plaques are being used more commonly in the treatment of melanomas of the choroid, and the role for radiation therapy in the management of retinoblastoma is changing markably to where it may be used as the primary treatment program rather than enucleation. In metastatic disease involving the uveal tract, radiation therapy has assumed the most important role for management. Chemotherapy should be considered as an active adjuvant in the management of not only those individuals with retinoblastoma but also in those identified circumstances where metastases to the uveal tract are being treated. The role for chemotherapy or immunotherapy in malignant melanoma is unclear.

摘要

放射治疗师在恶性眼内肿瘤治疗中的角色正在发生变化。随着对恶性眼内肿瘤的识别更加积极,以及对处理放射敏感性问题方式的更好认识,各种放射技术将更积极地应用于这些肿瘤的治疗。必须根据适当的治疗情况选择特殊技术,以将对晶状体、视力和角膜的影响降至绝对最低限度。钴 - 60 敷贴器在脉络膜黑色素瘤的治疗中使用得越来越普遍,放射治疗在视网膜母细胞瘤治疗中的作用正在显著改变,它可能被用作主要治疗方案而非眼球摘除术。在涉及葡萄膜的转移性疾病中,放射治疗在治疗中发挥着最重要的作用。化疗不仅应被视为视网膜母细胞瘤患者治疗中的一种积极辅助手段,而且在那些正在治疗葡萄膜转移的特定情况下也应如此。化疗或免疫疗法在恶性黑色素瘤中的作用尚不清楚。

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