The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
作者信息
Young S N, Gauthier S, Chouinard G, Anderson G M, Purdy W C
出版信息
J Neural Transm. 1982;53(1):83-7. doi: 10.1007/BF01243522.
PMID:6801200
Abstract
Peripheral aromatic amino acid decarboxylase inhibitors increase human plasma 5-hydroxytryptophan (5-HTP) levels. However the 5-HTP, which is synthesized in the intestine, is not present in a sufficient quantity to influence brain 5-HT to any significant degree. Thus, peripheral decarboxylase inhibitors are unlikely to affect brain 5-HT function via 5-HTP which is synthesized peripherally.
摘要
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