有机溶剂暴露人群的肾功能研究。IV. 对51-铬-乙二胺四乙酸清除率的影响。
Studies on kidney function in subjects exposed to organic solvents. IV. Effect on 51-Cr-EDTA clearance.
作者信息
Askergren A, Brandt R, Gullquist R, Silk B, Strandell T
出版信息
Acta Med Scand. 1981;210(5):373-6. doi: 10.1111/j.0954-6820.1981.tb09833.x.
Glomerular filtration rate (GFR) was studied by measuring the 51-Cr-EDTA clearance with single bolus injection technique in 107 men exposed to styrene, toluene or toluene and xylene in their professions and in 48 non-exposed male controls. The clearance values of the controls were significantly related both to body surface area (BSA) and age. These relations were used to calculate expected clearances for the exposed subjects. The clearances of the exposed subjects were on an average 3.8% higher than expected, according to BSA and age in this group. This divergence was not significant. Thus, no reduction in GFR was found in the subjects exposed to organic solvents.
采用单次大剂量注射技术，通过测量51-铬-乙二胺四乙酸清除率，对107名职业性接触苯乙烯、甲苯或甲苯与二甲苯的男性以及48名未接触的男性对照者的肾小球滤过率（GFR）进行了研究。对照组的清除率值与体表面积（BSA）和年龄均显著相关。利用这些关系计算出接触组受试者的预期清除率。根据该组的体表面积和年龄，接触组受试者的清除率平均比预期高3.8%。这种差异不显著。因此，未发现接触有机溶剂的受试者肾小球滤过率降低。
Zotero 插件