Strollo F, Riondino G, Torella G
Boll Soc Ital Biol Sper. 1981 Dec 30;57(24):2417-23.
Much confusion seems to exist on the timing and intensity of thyroid hormones (T4 and T3) response to TRH. As a first approach to the problem, the Authors performed TRH test in 5 healthy women. TSH showed a significant increase immediately after the TRH injection and kept high until the 90th minute. T3 decreased at first-still not significantly--then increased steadily and at 60 min it reached values significantly higher than the basal ones. Some increase was seen for T4 too, but it did not show to be statistically significant within 180 minutes. The Authors give revelance to the significance of precious (60 min) T3 increase in such a small casuistry.
关于甲状腺激素(T4和T3)对促甲状腺激素释放激素(TRH)反应的时间和强度似乎存在很多混淆。作为解决该问题的第一步,作者对5名健康女性进行了TRH测试。促甲状腺激素(TSH)在注射TRH后立即显著升高,并一直保持高位直至第90分钟。T3起初下降——仍不显著——然后稳步上升,在60分钟时达到显著高于基础值的值。T4也有一些升高,但在180分钟内未显示出统计学意义。作者强调了在如此小的病例组中宝贵的(60分钟时)T3升高的意义。