急性白血病治疗期间的甲状旁腺功能减退和低钙血症。
Hypoparathyroidism and hypocalcaemia during treatment for acute leukaemia.
作者信息
Freedman D B, Shannon M, Dandona P, Prentice H G, Hoffbrand A V
出版信息
Br Med J (Clin Res Ed). 1982 Mar 6;284(6317):700-2. doi: 10.1136/bmj.284.6317.700.
Abstract
Nine patients with acute leukaemia developed a complex syndrome of hypocalcaemia and hypomagnesaemia during treatment. These metabolic abnormalities developed rapidly in some patients and gave rise to acute symptoms. Immunoreactive parathormone concentrations in these patients were found to be either absolutely or inappropriately low. Hypomagnesaemia and the action of chemotherapeutic agents, especially adriamycin or cytarabine, or both may have contributed to the pathogenesis of this syndrome.
摘要
9例急性白血病患者在治疗期间出现了低钙血症和低镁血症的复杂综合征。这些代谢异常在一些患者中迅速出现并引发急性症状。发现这些患者的免疫反应性甲状旁腺激素浓度绝对或相对较低。低镁血症以及化疗药物尤其是阿霉素或阿糖胞苷的作用，或两者共同作用可能促成了该综合征的发病机制。
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本文引用的文献
1
Response to vitamin D of magnesium deficient rats.
Proc Soc Exp Biol Med. 1967 Jun;125(2):472-6. doi: 10.3181/00379727-125-32123.
2
Regulation of parathyroid hormone secretion in vitro: quantitative aspects of calcium and magnesium ion control.甲状旁腺激素分泌的体外调节：钙和镁离子控制的定量方面。
Endocrinology. 1971 Jun;88(6):1477-82. doi: 10.1210/endo-88-6-1477.
3
The influence of magnesium on calcium release from bone in vitro.镁对体外骨钙释放的影响。
Biochim Biophys Acta. 1970 Aug 14;215(2):360-7. doi: 10.1016/0304-4165(70)90035-8.
4
Secretion and metabolic efficacy of parthyroid hormone in patients with severe hypomagnesemia.严重低镁血症患者甲状旁腺激素的分泌及代谢效能
J Clin Endocrinol Metab. 1974 Mar;38(3):363-71. doi: 10.1210/jcem-38-3-363.
5
A quantitative ultrastructural study of microtubule content and secretory granule accumulation in parathyroid glands of phosphate- and colchicine-treated rats.对经磷酸盐和秋水仙碱处理的大鼠甲状旁腺中微管含量和分泌颗粒积累的定量超微结构研究。
J Clin Invest. 1975 Jul;56(1):49-55. doi: 10.1172/JCI108078.
6
Hypocalcemia with hypoparathyroidism and renal tubular dysfunction associated with aminoglycoside therapy.低钙血症伴甲状旁腺功能减退及与氨基糖苷类药物治疗相关的肾小管功能障碍。
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7
Immunoreactive calcitonin in leukaemia.白血病中的免疫反应性降钙素。
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8
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