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棉塞成分对淋病奈瑟菌生长和传播的影响。

Effects of tampon components on growth and dissemination of Neisseria gonorrhoeae.

作者信息

Arko R J, Wong K H, Finley-Price K G, Rasheed J K

出版信息

Br J Vener Dis. 1982 Apr;58(2):105-8. doi: 10.1136/sti.58.2.105.

DOI:10.1136/sti.58.2.105
PMID:6802439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1046017/
Abstract

Six components used in vaginal tampons were tested for their effects on a strain of Neisseria gonorrhoeae isolated from a patient with disseminated infection. Tampon components containing carboxymethyl cellulose or its derivative prolonged the in-vitro survival of gonococci and, when injected with mucin into mice, significantly (P less than 0.0001) increased the dissemination of gonococci from the peritoneal cavity. In contrast, a component extracted from rayon tampons reduced in-vitro survival and appeared to suppress gonococcal dissemination in mice. Since tampons are used by a large number of women at a time when the risk of developing complications from venereal infections are increased, their effects on potential urogenital pathogens warrant further study.

摘要

对阴道卫生棉条中使用的六种成分进行了测试,以观察它们对从一名患有播散性感染的患者身上分离出的一株淋病奈瑟菌的影响。含有羧甲基纤维素或其衍生物的卫生棉条成分延长了淋球菌在体外的存活时间,并且当与粘蛋白一起注射到小鼠体内时,显著(P小于0.0001)增加了淋球菌从腹腔的播散。相比之下,从人造丝卫生棉条中提取的一种成分缩短了体外存活时间,并且似乎抑制了小鼠体内淋球菌的播散。由于在发生性传播感染并发症的风险增加时,大量女性会使用卫生棉条,因此它们对潜在泌尿生殖病原体的影响值得进一步研究。

相似文献

1
Effects of tampon components on growth and dissemination of Neisseria gonorrhoeae.棉塞成分对淋病奈瑟菌生长和传播的影响。
Br J Vener Dis. 1982 Apr;58(2):105-8. doi: 10.1136/sti.58.2.105.
2
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引用本文的文献

1
Antigonococcal effects of vaginal tampons.阴道棉塞的抗淋球菌作用。
Br J Vener Dis. 1983 Apr;59(2):94-7. doi: 10.1136/sti.59.2.94.

本文引用的文献

1
STUDIES OF GONOCOCCAL INFECTION. IV. THE EFFECT OF MUCIN ON THE BACTERIOLYTIC POWER OF WHOLE BLOOD AND IMMUNE SERUM.淋病感染的研究。IV. 粘蛋白对全血和免疫血清溶菌能力的影响。
J Clin Invest. 1938 Jan;17(1):23-30. doi: 10.1172/JCI100924.
2
Toxic-shock syndrome in menstruating women: association with tampon use and Staphylococcus aureus and clinical features in 52 cases.经期女性中毒性休克综合征:与使用卫生棉条及金黄色葡萄球菌的关联及52例临床特征
N Engl J Med. 1980 Dec 18;303(25):1436-42. doi: 10.1056/NEJM198012183032502.
3
Toxic-shock syndrome: epidemiologic features, recurrence, risk factors, and prevention.中毒性休克综合征:流行病学特征、复发情况、危险因素及预防措施
N Engl J Med. 1980 Dec 18;303(25):1429-35. doi: 10.1056/NEJM198012183032501.
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Intrauterine device use and the risk of pelvic inflammatory disease.
Am J Obstet Gynecol. 1980 Dec 1;138(7 Pt 2):861-3. doi: 10.1016/0002-9378(80)91071-6.
5
Critical illnesses and deaths associated with intrauterine devices.与宫内节育器相关的重症疾病和死亡
Obstet Gynecol. 1968 Mar;31(3):322-7. doi: 10.1097/00006250-196803000-00003.
6
Disseminated gonococcal infection.播散性淋球菌感染
Ann Intern Med. 1971 Jun;74(6):979-93. doi: 10.7326/0003-4819-74-6-979.
7
Gonococcal salpingitis.淋菌性输卵管炎
Br J Vener Dis. 1969 Sep;45(3):205-15. doi: 10.1136/sti.45.3.205.
8
Disseminated gonococcal infection in mice.小鼠播散性淋球菌感染
Infect Immun. 1979 Dec;26(3):984-90. doi: 10.1128/iai.26.3.984-990.1979.
9
Studies on the mechanism of pathogenicity of Neisseria gonorrhoeae.
J Med Microbiol. 1977 Aug;10(3):347-65. doi: 10.1099/00222615-10-3-347.
10
Toxic-shock syndrome associated with phage-group-I Staphylococci.与噬菌体 I 群葡萄球菌相关的中毒性休克综合征。
Lancet. 1978 Nov 25;2(8100):1116-8. doi: 10.1016/s0140-6736(78)92274-2.