Salamero J, Michel-Béchet M, Charreire J
C R Seances Acad Sci III. 1981 Dec 14;293(14):745-50.
From day 9 to 15 of Thyroid Epithelial Cell (TEC) culture the expression of MHC antigens (K, D and Ia) was studied. Methods used for antigen detection included direct cytotoxicity in the presence of rabbit complement and electron microscopy using goat anti-mouse peroxidase-labeled Fab fragments. Results obtained showed that the K and D end-coded MHC antigens (class I) are exclusively expressed on the apical cell surface of TEC while Ia antigens (class II) are only found on the basal part of the cell.
在甲状腺上皮细胞（TEC）培养的第9天至第15天，对主要组织相容性复合体（MHC）抗原（K、D和Ia）的表达进行了研究。用于抗原检测的方法包括在兔补体存在下的直接细胞毒性试验，以及使用山羊抗小鼠过氧化物酶标记的Fab片段进行电子显微镜观察。所得结果表明，由K和D编码的MHC抗原（I类）仅在TEC的细胞顶端表面表达，而Ia抗原（II类）仅在细胞基部发现。
