Barboriak J J, Alaupovic P, Cushman P
Drug Alcohol Depend. 1981 Dec;8(4):337-43. doi: 10.1016/0376-8716(81)90042-9.
Plasma lipids, including total cholesterol, plasma triglycerides, high density lipoprotein cholesterol and several apolipoproteins were measured in eight otherwise healthy male alcoholics at the beginning and during a 4-week inpatient abstinence treatment program. The initial triglyceride and apolipoprotein A-11 levels were higher and apolipoprotein B was lower in alcoholics than in 12 nondrinking control subjects. During the alcohol abstinence there was a parallel fall in the levels of high density lipoprotein cholesterol, and apolipoproteins A-I and A-II and a rise in apolipoprotein B. The changes in apolipoproteins C-III and E were less consistent. These findings suggest that, even in otherwise healthy alcoholics, elevated levels of apolipoproteins A-I and A-II on admission are ameliorated during abstinence of several weeks.
在8名其他方面健康的男性酗酒者住院戒酒治疗项目开始时以及治疗期间，检测了包括总胆固醇、血浆甘油三酯、高密度脂蛋白胆固醇和几种载脂蛋白在内的血浆脂质。酗酒者的初始甘油三酯和载脂蛋白A-II水平高于12名非饮酒对照者，而载脂蛋白B水平低于非饮酒对照者。在戒酒期间，高密度脂蛋白胆固醇、载脂蛋白A-I和A-II水平平行下降，载脂蛋白B水平上升。载脂蛋白C-III和E的变化不太一致。这些发现表明，即使在其他方面健康的酗酒者中，入院时升高的载脂蛋白A-I和A-II水平在数周戒酒期间也会有所改善。
