黄曲霉毒素前体的致突变性和毒性。
Mutagenicity and toxicity of aflatoxin precursors.
作者信息
Dunn J J, Lee L S, Ciegler A
出版信息
Environ Mutagen. 1982;4(1):19-26. doi: 10.1002/em.2860040104.
PMID:6802632
Abstract
The Salmonella/microsome test and the chick embryo test were used to determine the mutagenicity and toxicity of five aflatoxin B1 precursors. A definite pattern emerges: the nearer the B1 an intermediate appears in the biosynthetic pathway, the more potent is its mutagenicity and toxicity.
摘要
采用沙门氏菌/微粒体试验和鸡胚试验来测定5种黄曲霉毒素B1前体的致突变性和毒性。一种明确的模式显现出来：在生物合成途径中，一种中间体越接近B1，其致突变性和毒性就越强。
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